In a landmark simulation, scientists have recreated the full cell cycle of a living cell in four dimensions — three dimensions plus time. Using a highly detailed digital model of a minimal synthetic ...

By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...

One of the holy grails of biology is digitally simulating a living cell. If researchers can use computers to more accurately understand how new medicines would react in the body, that could give them ...

A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life ...

Drug discovery requires experimental systems that more accurately capture the complexity of human tissues. However, animal models and conventional cell culture approaches often lack the physiological ...

Graham Johnson, a computational biologist and scientific illustrator at the Allen Institute for Cell Science, recalls fantasizing at a lunch table, more than 15 years ago, about a computer model of a ...

A vascularized organoid model of hormone-secreting cells in the pancreas has been developed, with potential to improve diabetes research and cell-based therapies. “Our results highlight the importance ...

Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...