Researchers demonstrate how mathematical modeling combined with dynamic biomarkers can be used to characterize metastatic disease and identify appropriate therapeutic approaches to improve patient ...

Mathematical models have become an integral part of cancer biology. They are useful tools for deriving a mechanistic understanding of dynamic processes in cancer. The somatic evolutionary process, ...

In a recent study posted to the Research Square* preprint server, researchers designed a dynamic mathematical model to simulate the transmission of the severe acute respiratory syndrome coronavirus 2 ...

Utilizing reduced-order dynamic math models (DMM) in linear system-level dynamic analyses is a well-known practice that enables extreme computational ...

TGF-β-induced Smad signal transduction from the membrane into the nucleus is not linear and unidirectional, but rather a dynamic network that couples Smad phosphorylation and dephosphorylation through ...

Shoulder dystocia (SD) is an obstetric emergency in which the neonate’s shoulder is impacted behind the symphysis pubis of the maternal pelvis. This is a highly unpredictable event, occurring in about ...

Why do we need to understand the dynamics of the cell cycle? The cell cycle is a mechanism that controls and integrates the stages of DNA synthesis, mitosis, and cell division. This mechanism dictates ...