Nature

Regions of homozygosity identified by SNP microarray analysis aid in the diagnosis of autosomal recessive disease and incidentally detect parental blood relationships

The purpose of this study was to document the ability of single-nucleotide polymorphism microarray to identify copy-neutral regions of homozygosity, demonstrate clinical utility of regions of ...
Nature

Patterns of homozygosity in patients with uniparental disomy: detection rate and suggested reporting thresholds for SNP microarrays

Single-nucleotide polymorphism (SNP) microarrays can easily identify whole-chromosome isodisomy but are unable to detect whole-chromosome heterodisomy. However, most cases of uniparental disomy (UPD) ...
Medscape

Microarray-Based Prenatal Diagnosis for the Identification of Fetal Chromosome Abnormalities

The sequencing of the human genome afforded the development of chromosomal microarrays that can be used to detect gains and losses of the genome. Microarrays are constructed from large pieces of ...
Labroots

Microarrays: an essential tool for Predictive Genomics

The human genome project was undertaken to determine the human DNA sequence and analyze variation among individuals. To make use of this information, tools were developed that could collect and ...