This Research Topic is the second volume of the “Unraveling Breast Cancer Complexity: Insights from Single-Cell Sequencing and Spatial Transcriptomics” ...

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to ...

Researchers create a massive single-cell atlas of the aging mouse brain, revealing how epigenetic changes and "jumping genes" drive neurodegeneration.

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...

AGBT is also, increasingly, a showcase for instruments for spatial biology, a fast-growing field that involves pinpointing the location of RNA and protein molecules en masse. Tarbox calls the meeting ...

Single-cell omics is a transformative area within life sciences, enabling researchers to untangle cellular heterogeneity, uncover developmental lineages, ...

We introduce a novel deep learning framework, SpaGene, which integrates scRNA-seq data and spatial transcriptomics data through an encoder-decoder architecture with translators, and discriminators, ...

Prostate cancer: Correlating the clinical phenotype to the genotype. Association of a post-prostatectomy digital pathology–based multimodal artificial intelligence (MMAI) biomarker with nodal and ...

Use of ultra-sensitive whole genome circulating tumor DNA detection to predict early recurrence in high-risk localized RCC after nephrectomy: Preliminary real-world findings. Forty-two genes ...

Abstract: Spatial transcriptomics has revolutionized the ability to investigate transcriptional patterns within tissue morphology. However, many ST clustering pipelines operate on a single preselected ...